Jan’s career in interdisciplinary science spans man years. Her research has involved: bioluminescence, inflammatory diseases, free radicals, cardiovascular diseases, biocompatibility of medical devices, antioxidants and diet, measuring antioxidant activity, monitoring the health and performance of elite athletes and in developing methods for use in such research.
She co-founded Knight Scientific Ltd (KSL) to exploit the potential of the bioluminescent protein Pholasin® an exquisitely sensitive detector of free radicals and other reactive oxygen species, unique to KSL. Under her leadership as Managing Director, KSL develops, manufactures and markets a number of analytical and diagnostic research kits, carries out contract testing and research and has come to be recognized as a world leader in products for free radical research. ABEL® (Analysis By Emitted Light) kits are all based on Pholasin® and are used in research into oxidative stress which embraces applications into over 150 free radical-mediated diseases, including cancer, diabetes, and heart disease. ABEL® kits are also now routinely used for QC of products and for monitoring the well-being of people, especially elite athletes.
Jan has been an invited speaker at international conferences and has given seminars and practical workshops at pharmaceutical and medical device companies, the Olympic Medical Institute, and at the National Measurement Institute of Australia. She gave a lecture at the British Association of Sports Exercise Medicine (BASEM) conference and presented two papers at the Isokinetic and FIFA, Football Medicine Conferences.
She won five SMART awards for KSL; led a consortium under the DTI’s Wealth from the Oceans programme; led a prestigious Health Technology Devices collaborative project is a member of an Horizon 2020 five partner consortium. She collaborates with scientists and clinicians in many universities and hospitals in the UK and abroad, is a visiting fellow at Plymouth Marjon University and is an inventor of a number of patents. In 1999 she became a lifetime Millennium Fellow.